NUP153 antibody

Catalog No. ABIN7117045

This Rabbit Polyclonal antibody specifically detects NUP153 in WB and ELISA. It exhibits reactivity toward Human, Rat and Mouse.

Quick Overview for NUP153 antibody (ABIN7117045)

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NUP153 antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Product Details anti-NUP153 Antibody

Purpose: NUP153 antibody

Purification: Immunogen affinity purified

Purity: ≥95 % as determined by SDS-PAGE

Immunogen: nucleoporin 153kDa

Isotype: IgG

Application Details

Application Notes: WB: 1:500-1:2000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS with 0.02 % sodium azide and 50 % glycerol pH 7.3,

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze / thaw cycles.

Storage: -20 °C

Storage Comment: -20°C for 12 months

Expiry Date: 12 months

Target Details for NUP153

Target: NUP153 (Nucleoporin 153kDa (NUP153))

Alternative Name: NUP153

Background:

Synonyms: Nuclear pore complex protein Nup153|153 kDa nucleoporin|Nucleoporin Nup153|NUP153

Background: Component of the nuclear pore complex(NPC), a complex required for the trafficking across the nuclear envelope. Functions as a scaffolding element in the nuclear phase of the NPC essential for normal nucleocytoplasmic transport of proteins and mRNAs. Involved in the quality control and retention of unspliced mRNAs in the nucleus, in association with TPR, regulates the nuclear export of unspliced mRNA species bearing constitutive transport element(CTE) in a NXF1-and KHDRBS1-independent manner. Mediates TPR anchoring to the nuclear membrane at NPC. The repeat-containing domain may be involved in anchoring other components of the NPC to the pore membrane. Possible DNA-binding subunit of the nuclear pore complex(NPC).

Molecular Weight: 153 kDa

Gene ID: 9972

UniProt: P49790

Pathways: Protein targeting to Nucleus